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Belzutifan

CAT: 0931-T16679-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16679-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1672668-24-4
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
Purity
0.9988
Bioactivity
Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC) . Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM) . Belzutifan , as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
Smiles
CS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2[C@@H](F)[C@@H](F)[C@@H](O)c12
Molecular Formula
C17H12F3NO4S
Molecular Weight
383.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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