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PS315

CAT: 0931-T16671-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16671-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1221964-50-6
Target
PKC
Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic
Bioactivity
PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM) . PS315 has anti-cancer activity. PS315 is a derivative of PS48 and is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing displacement of the active site residue Lys111.
Smiles
C(\CCC1=CC=C(Cl)C=C1)(=C/C(O)=O)/C2=CC=C(C=C2)C3=CC=CC=C3
Molecular Formula
C23H19ClO2
Molecular Weight
362.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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