Propargyl-PEG4-acid

• Target :

  Others|||PROTAC Linker

• Related Pathways :

  Others|||PROTAC

• Bioactivity :

  Propargyl-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and its analogue PROTAC 3. PROTAC 3 induces BTK degradation with a DC50 of 200 nM in THP-1 cells[1].

• Smiles :

  C(OCCOCCOCC#C)COCCC(O)=O

• Molecular Formula :

  C12H20O6

• Molecular Weight :

  260.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1415800-32-6