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Propargyl-PEG1-acid

CAT: 0931-T16583-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T16583-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55683-37-9
Target
PROTAC Linker, Others
Related Pathways
Others, PROTAC
Bioactivity
Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1].
Smiles
OC(=O)CCOCC#C
Molecular Formula
C6H8O3
Molecular Weight
128.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C