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PRN694

CAT: 0931-T16578-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16578-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1575818-46-0
Target
Others, Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
PRN694 shows extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo. PRN694 is an irreversible, highly selective, and effective covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor (IC50s: 0.3 nM and 1.4 nM, respectively) .
Smiles
C[C@H](NCc1ccc2n(C[C@H]3CCCN3C(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C
Molecular Formula
C28H35F2N5O2S
Molecular Weight
543.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA8983-5PRN694
A16998-100PRN694 100mg
A16998-5PRN694 5mg
A16998-50PRN694 50mg
A16998-25PRN694 25mg
A16998-10PRN694 10mg
A16998-1PRN694 1mg

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