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Pozanicline

CAT: 0931-T16563-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16563-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
161417-03-4
Target
AChR
Related Pathways
Neuroscience
Bioactivity
Pozanicline reverses nicotine withdrawal-induced cognitive deficits, may be an effective component of novel therapeutic strategies for nicotine addiction. Pozanicline selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM) . It shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM .
Smiles
O(C[C@@H]1CCCN1)C2=C(C)N=CC=C2
Molecular Formula
C11H16N2O
Molecular Weight
192.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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