PG01

CAT: 0931-T16516-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T16516-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

853138-65-5

Target

CFTR

Related Pathways

Membrane transporter/Ion channel

Purity

0.9987

Bioactivity

PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 increases ΔF508-CFTR Cl- currents upon addition of forskolin. F508-CFTR Cl-current upon addition of Forskolin, correcting the gating defect of CFTR mutants.

Smiles

CC(C)c1ccc(NC(=O)C(N(C)C(=O)Cc2c[nH]c3ccccc23)c2ccccc2)cc1

Molecular Formula

C28H29N3O2

Molecular Weight

439.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
M33463-01	PG01
LYSKITPG01	Bead Lysis Kit PG01

Popular Products

Human Endometrial Epithelial Cell Complete Medium
SKU: MBS2576753-01|Size: 100 mL
Human Endometrial Menstrual Cells
SKU: ABC-TC3601|Size: 1 Vial
Varicella Zoster Virus Glycoprotein E (VZV gE) ELISA Kit (For Vaccine Development)
SKU: RAS-A185-96tests|Size: 96 Tests
Human Endometrial Epithelial Cells
SKU: ABC-TC4601|Size: 1 Vial
Neptune Pipette Tips 0.5-10 µL XL Universal Fit Racked, Low-Retention, Pre-Sterilized
SKU: 2342S3.S|Size: 10/PACK, 5/CASE
Neptune Pipette Tips 0.5-10 µL XL Universal Fit Racked, Low-Retention
SKU: 2342S3|Size: 10/PACK, 5/CASE
Transcobalamin-2
SKU: GTR19020428-01|Size: 50 µg
Neptune Filter Tips 0.5-10 µL XL Universal Fit Racked, Pre-Sterilized, NOLO
SKU: BT10XL|Size: 96 Tips/Rack - 10 Racks/PK
Naphthaleneacetic Acid (NAA) Solution 1mg/mL, Sterile
SKU: NSL01-100ML|Size: 100 mL
Naphthaleneacetic Acid (NAA)
SKU: CN-N001-100GM|Size: 100 g

Lymphoma tissue array with adjacent normal lymph node and spleen tissue as control, 80 cases/80 cores, replacing LM801a
SKU: LM801b|Size: 1 Each
Tissue, Western Blot, Human Adult Normal, Blot IV, heart, brain, kidney, liver, lung, pancreas, spleen, skeletal muscle, stomach, small intestine, colon, rectum, uterus, prostate, testis, placenta
SKU: MBS639755-01|Size: 1 Blot
Tissue, Array, Human Disease (Adult), Lymphoma, Axillary Lymph Node, Colon, Leg, Lung, Lymph Node, Mesenteric Site, Neck, Ovary, Pelvic, Peritoneal Cavity, Shoulder, Small Intestine, Stomach, Testis, Thyroid, Tonsil (Paraffin)
SKU: MBS639536-01|Size: 5 Slides
Tissue, Array, Human Adult Normal, Multi, tissue (8) III, Major Organ, Tonsil, Thymus, Appendix, Lymph node, Gallbladder, Prostate, Testis, Ovary (Paraffin)
SKU: MBS639683-01|Size: 5 Arrays
Immune multiple organs tumor and normal tissue array, containing 20 cases leukemia, 20 cases non-Hodgkin's lymphoma, 20 cases Hodgkin's lymphoma, 11 cases plasma cell myeloma, 9 cases extramedullary plasmacytoma, 20 cases malignant thymoma, plus 2 each cases of normal lymph node, spleen, bone marrow and thymus gland tissue, 108 cases/108 cores
SKU: MC1081|Size: 1 Each
Tissue, Array, Human Adult Normal, Multi, tissue (8) I, Major Organ, Heart, Brain, Kidney, Liver, Lung, Pancreas, Spleen, Skeletal Muscle (Paraffin)
SKU: MBS639687-01|Size: 5 Arrays
Tissue, Array, Human Tumor (Adult), Multiple Tumor, Brain, Breast, Colon, Liver, Lung, Placenta, Prostate, Scalp, Tonsil, Thymus, Thyroid, Uterus (Paraffin)
SKU: MBS639722-01|Size: 5 Slides
Tissue, Array, Human Tumor, Different Types of Tumor, Multi, tissue VI (8), breast, control, uterus, control, teratoma/fallopian tube, control, ovary, control (matched with Total RNA Northern Blot) (Paraffin)
SKU: MBS639445-01|Size: 5 Arrays
Her-2 IHC Bio-marker control tissue array of breast invasive ductal carcinoma, including pathology grade, TNM and clinical stage, 10 cases/ 10 cores.
SKU: Her2d|Size: 1 Each
Tissue, Array, Human Disease (Adult), Cardiovascular, Aorta, Artery, Heart, Kidney, Large Vein, Left Atrium, Leg, Liver, Lymph Node, Main Artery, Nasocavity, Pericardium, Placenta, Skin, Spleen, Stomach, Umbilical Cord, Vein (Paraffin)
SKU: MBS639408-01|Size: 5 Slides