PF-4693627

• Target:

  PGE Synthase|||Prostaglandin Receptor

• Related Pathways:

  GPCR/G Protein|||Immunology/Inflammation

• Bioactivity:

  PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM) . It is used for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA) .

• Smiles:

  ClC=1C=C2C(OC(=N2)N3CCC(C(N[C@@H]4C[C@@H](CO)CCC4)=O)CC3)=CC1C5=CC=C(Cl)C=C5

• Molecular Formula:

  C26H29Cl2N3O3

• Molecular Weight:

  502.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1312815-93-2