PF-05085727

• Target :

  PDE

• Related Pathways :

  Metabolism

• Bioactivity :

  PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .

• Smiles :

  Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(cc1)C(F)(F)F

• Molecular Formula :

  C20H18F3N7

• Molecular Weight :

  413.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1415637-72-7