PF-05085727

• Target:

  PDE

• Related Pathways:

  Metabolism

• Bioactivity:

  PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. PF-05085727 is an effective, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) .

• Smiles:

  Cn1ncc (-c2nn (C) c3ncnc (N4CCC4) c23) c1-c1ccc (cc1) C (F) (F) F

• Molecular Formula:

  C20H18F3N7

• Molecular Weight:

  413.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1415637-72-7