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PF-04447943

CAT: 0931-T16478-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16478-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1082744-20-4
Target
PDE
Related Pathways
Metabolism
Purity
0.9959
Bioactivity
PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM) .PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.
Smiles
C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Molecular Formula
C20H25N7O2
Molecular Weight
395.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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