Okadaic acid

• Target:

  Phosphatase

• Related Pathways:

  Metabolism

• Bioactivity:

  Okadaic acid is a potent polyether marine toxin that primarily accumulates in the digestive glands of marine mollusks. It is a highly effective and selective inhibitor of protein phosphatases (PPs) . By inhibiting these phosphatases, okadaic acid increases the phosphorylation levels of various proteins, acts as a tumor promoter, and induces tau protein phosphorylation. It can be used to establish models of Alzheimer’s disease and skin cancer.

• Smiles:

  O[C@H]1[C@@]2 (O[C@] ([C@@H] (/C=C/[C@@H]3O[C@]4 (CC3) O[C@@]5 ([C@@] (CC4) (O[C@] ([C@H] (C[C@H] (C) [C@]6 (O[C@]7 (CC[C@H]6C) CCCCO7) [H]) O) (C (=C) [C@H]5O) [H]) [H]) [H]) C) (CC (C) =C2) [H]) O[C@H] (C[C@@] (C (O) =O) (C) O) CC1

• Molecular Formula:

  C44H68O13

• Molecular Weight:

  805

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  78111-17-8