NVP-2

• Target :

  Apoptosis|||CDK

• Related Pathways :

  Apoptosis|||Cell Cycle/Checkpoint

• Purity :

  0.9976

• Bioactivity :

  NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM) . NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 ?M, 0.706 ?M, and 0.605 ?M, respectively) .

• Smiles :

  COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1

• Molecular Formula :

  C27H37ClN6O2

• Molecular Weight :

  513.07

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1263373-43-8