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NS13001

CAT: 0931-T16345-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T16345-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1063331-94-1
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9955
Bioactivity
NS13001 (N- (4-Chlorophenyl) -2- (3,5-dimethyl-1H-pyrazol-1-yl) -9-methyl-9H-purin-6-amine) is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels) . The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.
Smiles
Cc1cc(C)n(n1)-c1nc(Nc2ccc(Cl)cc2)c2ncn(C)c2n1
Molecular Formula
C17H16ClN7
Molecular Weight
353.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA6902-25NS13001
A15833-100NS13001 100mg
A15833-10NS13001 10mg
A15833-50NS13001 50mg
A15833-25NS13001 25mg
A15833-5NS13001 5mg
A15833-2NS13001 2mg
A15833-10mM-DNS13001 10mM * 1mL in DMSO

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