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NKH477

CAT: 0931-T16332Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T16332Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
138605-00-2
Target
AChR
Related Pathways
Neuroscience
Purity
0.98
Bioactivity
NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity. It inhibits ACh-induced Ca2+ mobilization by acting on ionomycin-sensitive storage sites. NKH477 is an adenylyl cyclase activator with bronchodilatory effects, inhibiting the production of CTL, T-cell proliferation in mixed lymphocyte reactions (MLR), as well as IL-2 production and mitogen responses.
Smiles
O[C@@]12[C@]3(C)[C@@]([C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H].Cl
Molecular Formula
C27H44ClNO8
Molecular Weight
546.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C