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Nebicapone

CAT: 0931-T16279-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16279-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
274925-86-9
Target
Transferase, Others
Related Pathways
Others, Metabolism
Bioactivity
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor and is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT. It is the potential for the treatment of Parkinson's disease.
Smiles
Oc1cc(cc(c1O)[N+]([O-])=O)C(=O)Cc1ccccc1
Molecular Formula
C14H11NO5
Molecular Weight
273.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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