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Marizomib

CAT: 0931-T16012-01Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0931-T16012-01Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
437742-34-2
Target
Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome
Purity
0.9941
Bioactivity
Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM.[3]
Smiles
[C@@H](O)([C@]12[C@](C)([C@@H](CCCl)C(=O)N1)OC2=O)[C@]3(CCCC=C3)[H]
Molecular Formula
C15H20ClNO4
Molecular Weight
313.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C