RegisterLogin

Manumycin A

CAT: 0931-T16011-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T16011-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
52665-74-4
Target
ATG|||Ras|||Phospholipase|||Reductase|||Apoptosis|||TNF|||Antibiotic|||Transferase
Related Pathways
MAPK|||Metabolism|||Autophagy|||GPCR/G Protein|||Microbiology/Virology|||Endocrinology/Hormones|||Apoptosis
Bioactivity
Manumycin A is an antibiotic with anticancer activity and is a mammalian thioredoxin reductase-1 (TrxR-1) inhibitor.Manumycin A inhibits the production of IL-1?, IL-6, and IL-8 in TNF alpha-stimulated THP-1 cells and peripheral blood mononuclear cells in a dose-dependent manner, inducing apoptosis.
Smiles
[H][C@]12O[C@@]1([H])[C@](O)(\C=C\C=C\C=C\C(=O)NC1=C(O)CCC1=O)C=C(NC(=O)C(\C)=C\C(\C)=C\[C@H](C)CCCC)C2=O
Molecular Formula
C31H38N2O7
Molecular Weight
550.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName

Alternative Products

CatalogName
TRC-M186000-2.5MGManumycin A
207274Manumycin B
207273-01Manumycin A discontinued
A24523-10Manumycin A 10mg
A24523-50Manumycin A 50mg
HY-N14342Manumycin E
A24523-1Manumycin A 1mg

Popular Products