LP-935509

• Target:

  AAK1|||AAK1 (AP2 associated kinase 1) |||Serine/threonin kinase|||SARS-CoV

• Related Pathways:

  Microbiology/Virology|||Metabolism|||Cell Cycle/Checkpoint|||Neuroscience

• Purity:

  0.9964

• Bioactivity:

  LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1) with an IC50 of 3.3 nM and a Ki of 0.9 nM. LP-935509 is a potent inhibitor of BIKE (IC50 of 14 nM) and a moderate inhibitor of GAK (IC50 of 320±40 nM) .

• Smiles:

  COc1ncccc1-c1cnn2ccc(nc12)N1CCN(CC1)C(=O)OC(C)C

• Molecular Formula:

  C20H24N6O3

• Molecular Weight:

  396.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1454555-29-3