LLY-283

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9949

• Bioactivity:

  LLY-283 is a potent, selective, and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, exhibiting an IC50 of 22 nM and a Kd of 6 nM for the PRMT5:MEP50 complex, and demonstrates antitumor activity.

• Smiles:

  [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1

• Molecular Formula:

  C17H18N4O4

• Molecular Weight:

  342.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2040291-27-6