LLY-283

• Target :

  Histone Methyltransferase

• Related Pathways :

  Chromatin/Epigenetic

• Purity :

  0.9949

• Bioactivity :

  LLY-283 is a potent, selective, and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, exhibiting an IC50 of 22 nM and a Kd of 6 nM for the PRMT5:MEP50 complex, and demonstrates antitumor activity.

• Smiles :

  [H][C@@]1(O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)[C@H](O)c1ccccc1

• Molecular Formula :

  C17H18N4O4

• Molecular Weight :

  342.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2040291-27-6