Etoricoxib

• Target:

  COX

• Related Pathways:

  Immunology/Inflammation|||Neuroscience

• Purity:

  0.9987

• Bioactivity:

  Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

• Smiles:

  CC1=NC=C(C=C1)C1=NC=C(Cl)C=C1C1=CC=C(C=C1)S(C)(=O)=O

• Molecular Formula:

  C18H15ClN2O2S

• Molecular Weight:

  358.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  202409-33-4