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Larotaxel

CAT: 0931-T15713-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15713-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
156294-36-9
Target
P-gp, Apoptosis
Related Pathways
Apoptosis, Membrane transporter/Ion channel, Neuroscience
Purity
0.9922
Bioactivity
Larotaxel (XRP9881) is a taxane analogue with anticancer activity that promotes tubulin assembly and stabilizes microtubules, inducing apoptosis. It crosses the blood-brain barrier and has a higher affinity for Docetaxel than P-glycoprotein 1, making it useful for studying breast and bladder cancer.
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[H][C@@]12C[C@@H]3C[C@@]33C(=O)[C@]([H])(OC(C)=O)C4=C(C)[C@@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1
Molecular Formula
C45H53NO14
Molecular Weight
831.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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