K-252c

• Target:

  PKC|||Apoptosis|||Antibacterial

• Related Pathways:

  Apoptosis|||Microbiology/Virology|||Cytoskeletal Signaling|||Chromatin/Epigenetic

• Bioactivity:

  K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 ?M) . K-252c also inhibits ?-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.

• Smiles:

  O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

• Molecular Formula:

  C20H13N3O

• Molecular Weight:

  311.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  85753-43-1