JTK-853

• Target :

  Others|||HCV Protease

• Related Pathways :

  Others|||Microbiology/Virology|||Proteases/Proteasome

• Bioactivity :

  JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase, exhibiting effective antiviral activity in HCV replicon cells with EC50s of 0.38 ?M for genotype 1a H77 strain and 0.035 ?M for genotype 1b Con1 strain.

• Smiles :

  C(NCC1=CC(F)=C(OC(F)(F)F)C=C1)(=O)[C@@H]2N(S(=O)(=O)C3=CC=C(C(F)(F)F)C=C3)CCN(C2)C4=NC=5C(S4)=CN=C(N5)C6CC6

• Molecular Formula :

  C28H23F7N6O4S2

• Molecular Weight :

  704.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  954389-09-4