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JND3229

CAT: 0931-T15615-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15615-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2260886-64-2
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Purity
0.9875
Bioactivity
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
Smiles
CCC(=O)N[C@H]1CC[C@@H](CC1)N1C(=O)N(Cc2cnc(Nc3ccc(N4CCN(C)CC4)c(C)c3)nc12)c1ccccc1Cl
Molecular Formula
C33H41ClN8O2
Molecular Weight
617.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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C12286-01JND3229
A24179-50JND3229 50mg
A24179-10JND3229 10mg
A24179-100JND3229 100mg
A24179-5JND3229 5mg

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