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IN-1130

CAT: 0931-T15572-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T15572-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
868612-83-3
Target
ALK, TGF-beta/Smad
Related Pathways
Tyrosine Kinase/Adaptors, Stem Cells, Angiogenesis
Purity
0.9979
Bioactivity
IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 μM for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38α mitogen-activated protein kinase.
Smiles
Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1
Molecular Formula
C25H20N6O
Molecular Weight
420.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C