IN-1130

• Target:

  ALK|||TGF-beta/Smad

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Stem Cells|||Angiogenesis

• Purity:

  0.9979

• Bioactivity:

  IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 ?M for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38? mitogen-activated protein kinase.

• Smiles:

  Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1

• Molecular Formula:

  C25H20N6O

• Molecular Weight:

  420.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  868612-83-3