Products for Research Use Only

IDH889

CAT: 0931-T15551-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15551-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429179-07-6
Target
Isocitrate Dehydrogenase (IDH), Dehydrogenase
Related Pathways
Metabolism
Purity
≥98%
Bioactivity
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt) .
Smiles
CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ncc(cn2)-c2ccc(F)c(C)c2)n1
Molecular Formula
C23H25FN6O2
Molecular Weight
436.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C