Icatibant

• Target:

  Bradykinin Receptor|||Others

• Related Pathways:

  Others|||GPCR/G Protein

• Bioactivity:

  Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively) .

• Smiles:

  N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](Cc1cccs1)C(=O)N[C@@H](CO)C(=O)NC(=N)NCCC[C@H](N(C(=O)C1C[C@@H]2CCCC[C@@H]2N1)C(=O)[C@H]1Cc2ccccc2CN1)C(O)=O

• Molecular Formula:

  C59H89N19O13S

• Molecular Weight:

  1304.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  130308-48-4