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Doxepin hydrochloride

CAT: 0931-T1540-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T1540-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1229-29-4
Target
Adrenergic Receptor, AChR, Norepinephrine, Cytochromes P450, 5-HT Receptor, Dopamine Receptor, Histamine Receptor
Related Pathways
GPCR/G Protein, Metabolism, Neuroscience, Immunology/Inflammation
Purity
0.9991
Bioactivity
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H (1) - and H (2) -receptors.
Smiles
Cl.CN(C)CCC=C1c2ccccc2COc2ccccc12
Molecular Formula
C19H22ClNO
Molecular Weight
315.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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