Foropafant

CAT: 0931-T15338-02Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T15338-02Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

136468-36-5

Target

PAFR, Platelet aggregation

Related Pathways

GPCR/G Protein, Others

Purity

0.9967

Bioactivity

Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM) . Foropafant potently inhibits the PAF-induced aggregation of rabbit and human platelets.

Smiles

CC(C)c1cc(C(C)C)c(-c2csc(n2)N(CCN(C)C)Cc2cccnc2)c(c1)C(C)C

Molecular Formula

C28H40N4S

Molecular Weight

464.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Foropafant

Foropafant is a small molecule drug. The usage of the INN stem '-pafant' in the name indicates that Foropafant is a platelet-activating factor antagonist. Foropafant has a monoisotopic molecular weight of 464.3 Da.

CAS Number	136468-36-5
PubChem CID	119368
IUPAC Name	N,N-dimethyl-N'-(pyridin-3-ylmethyl)-N'-[4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl]ethane-1,2-diamine
Molecular Formula	C28H40N4S
Molecular Weight	464.7
XLogP	6.9
Topological Polar Surface Area	60.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Heavy Atom Count	33
Formal Charge	0
Complexity	548

SMILES

CC(C)C1=CC(=C(C(=C1)C(C)C)C2=CSC(=N2)N(CCN(C)C)CC3=CN=CC=C3)C(C)C

InChI

InChI=1S/C28H40N4S/c1-19(2)23-14-24(20(3)4)27(25(15-23)21(5)6)26-18-33-28(30-26)32(13-12-31(7)8)17-22-10-9-11-29-16-22/h9-11,14-16,18-21H,12-13,17H2,1-8H3

InChIKey

VVBFISAUNSXQGZ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 136468-36-5

CID: 119368

Formula: C28H40N4S

MW: 464.7

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	464.7
XLogP3	6.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	464.29736847
Monoisotopic Mass	464.29736847
Topological Polar Surface Area	60.5 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	548
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BA5693-100	Foropafant
A13388-100	Foropafant 100mg
A13388-25	Foropafant 25mg
A13388-50	Foropafant 50mg
A13388-200	Foropafant 200mg
A13388-10	Foropafant 10mg
A13388-1	Foropafant 1mg
A13388-5	Foropafant 5mg
A13388-10mM-D	Foropafant 10mM * 1mL in DMSO

Foropafant

Chemical Information

Alternative Products

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