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Vactosertib Hydrochloride

CAT: 0931-T15262-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15262-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1352610-25-3
Target
ALK, TGF-beta/Smad
Related Pathways
Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors
Purity
0.9803
Bioactivity
Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an orally active and highly efficient ATP-competitive ALK5 (activin receptor-like kinase 5) inhibitor, a TGF-β receptor I inhibitor with anti-metastatic and anticancer properties. It sensitizes pancreatic cancer cells to gemcitabine by inhibiting their viability.
Smiles
Cl.FC=1C=CC=CC1NCC2=NC(C3=NC(=CC=C3)C)=C(N2)C=4C=CC5=NC=NN5C4
Molecular Formula
C22H19ClFN7
Molecular Weight
435.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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