Nilotinib

• Target:

  Autophagy|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Autophagy

• Purity:

  >99.99%

• Bioactivity:

  Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor with oral activity. Nilotinib has antitumor activity and may be used for the treatment of Imatinib-resistant chronic myelogenous leukemia (CML) .

• Smiles:

  C(F)(F)(F)C=1C=C(C=C(NC(=O)C2=CC(NC=3N=C(C=CN3)C=4C=CC=NC4)=C(C)C=C2)C1)N5C=NC(C)=C5

• Molecular Formula:

  C28H22F3N7O

• Molecular Weight:

  529.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  641571-10-0