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Dolastatin 15

CAT: 931-T15158-01Size: 100 mgDry Ice: NoHazardous: No
100 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
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CAS Number
123884-00-4
Target
Apoptosis|||ADC Cytotoxin|||Microtubule Associated
Related Pathways
Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related|||Apoptosis
Bioactivity
Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces cell cycle arrest and apoptosis in multiple myeloma cells.
Smiles
COC1=CC(=O)N([C@H]1Cc1ccccc1)C(=O)[C@@H](OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C|t:2,@:48,@@:36|
Molecular Formula
C45H68N6O9
Molecular Weight
837.072
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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