Dolastatin 15

• Target :

  Apoptosis|||ADC Cytotoxin|||Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related|||Apoptosis

• Bioactivity :

  Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces cell cycle arrest and apoptosis in multiple myeloma cells.

• Smiles :

  COC1=CC(=O)N([C@H]1Cc1ccccc1)C(=O)[C@@H](OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C|t:2,@:48,@@:36|

• Molecular Formula :

  C45H68N6O9

• Molecular Weight :

  837.072

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  123884-00-4