Dolastatin 15

CAT: 0931-T15158-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T15158-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

123884-00-4

Target

Apoptosis, ADC Cytotoxin, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related, Apoptosis

Bioactivity

Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces cell cycle arrest and apoptosis in multiple myeloma cells.

Smiles

COC1=CC(=O)N([C@H]1Cc1ccccc1)C(=O)[C@@H](OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C |t:2,@:48,@@:36|

Molecular Formula

C45H68N6O9

Molecular Weight

837.072

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
4019226.0001	Dolastatin 15
MBS3845703-01	Dolastatin 10
447637	Dolastatin 10 Trifluoroacetate
MBS130416-01	Monomethyl Dolastatin 10
A21273-5	Dolastatin 10 5mg
A21273-25	Dolastatin 10 25mg
A21273-2	Dolastatin 10 2mg

Dolastatin 15

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