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Streptozotocin

CAT: 0931-T1507-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T1507-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
18883-66-4
Target
Autophagy, DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibiotic, Antibacterial
Related Pathways
Cell Cycle/Checkpoint, Autophagy, DNA Damage/DNA Repair, Microbiology/Virology
Purity
>99.99%
Bioactivity
Streptozotocin (Streptozocin, NSC-85998) is an antibiotic that enters pancreatic β-cells via the glucose transporter (GLUT2) and induces DNA methylation, leading to β-cell apoptosis. It is toxic to insulin-producing cells and commonly used to establish diabetic animal models. This product is unstable in solution and is recommended to be prepared freshly before use.
Smiles
[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)(NC(N(N=O)C)=O)C=O
Molecular Formula
C8H15N3O7
Molecular Weight
265.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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