D5D-IN-326

• Target :

  Others|||Stearoyl-CoA Desaturase (SCD)

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays) . It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.

• Smiles :

  FC(F)(F)COc1ccc(cc1)-n1c(OCC(F)(F)C(F)(F)F)nc2NC(=O)Cc2c1=O

• Molecular Formula :

  C17H11F8N3O4

• Molecular Weight :

  473.27

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1236767-85-3