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CUDC-427

CAT: 0931-T15018-02Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15018-02Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1446182-94-0
Target
IAP
Related Pathways
Apoptosis
Purity
0.9992
Bioactivity
CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins (IAPs) . CUDC-427 can be used in research on cancers.
Smiles
CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)Nc1sc(nc1-c1ccccc1)-c1ncco1
Molecular Formula
C29H36N6O4S
Molecular Weight
564.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Gdc-0917

CUDC-427 has been used in trials studying the treatment of LYMPHOMA and Solid Cancers.

CAS Number1446182-94-0
PubChem CID71600094
IUPAC Name(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[2-(1,3-oxazol-2-yl)-4-phenyl-1,3-thiazol-5-yl]pyrrolidine-2-carboxamide
Molecular FormulaC29H36N6O4S
Molecular Weight564.7
XLogP4
Topological Polar Surface Area158
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Heavy Atom Count40
Formal Charge0
Complexity883
SMILES
C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C(=O)NC3=C(N=C(S3)C4=NC=CO4)C5=CC=CC=C5)NC
InChI
InChI=1S/C29H36N6O4S/c1-18(30-2)24(36)32-23(20-12-7-4-8-13-20)29(38)35-16-9-14-21(35)25(37)34-27-22(19-10-5-3-6-11-19)33-28(40-27)26-31-15-17-39-26/h3,5-6,10-11,15,17-18,20-21,23,30H,4,7-9,12-14,16H2,1-2H3,(H,32,36)(H,34,37)/t18-,21-,23-/m0/s1
InChIKey
HSHPBORBOJIXSQ-HARLFGEKSA-N
Chemical Structure
2D Structure
2D structure of Gdc-0917
CAS: 1446182-94-0
CID: 71600094
Formula: C29H36N6O4S
MW: 564.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight564.7
XLogP34
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count9
Exact Mass564.25187482
Monoisotopic Mass564.25187482
Topological Polar Surface Area158 Ų
Heavy Atom Count40
Formal Charge0
Complexity883
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS5754747CUDC-427
A20943-10CUDC-427 10mg
A20943-2CUDC-427 2mg
A20943-1CUDC-427 1mg
A20943-100CUDC-427 100mg
A20943-50CUDC-427 50mg
A20943-25CUDC-427 25mg
A20943-5CUDC-427 5mg
205468GDC-0917 (CUDC-427)
A20943-10mM-DCUDC-427 10mM * 1mL in DMSO

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