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Conteltinib

CAT: 0931-T14997-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14997-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1384860-29-0
Target
FAK, PYK2, ALK
Related Pathways
Angiogenesis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Purity
0.9954
Bioactivity
Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.
Smiles
COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCN(C)CC1
Molecular Formula
C32H45N9O3S
Molecular Weight
635.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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