Concanamycin A

• Target :

  Proton pump|||HIV Protease|||Antibiotic|||Antibacterial

• Related Pathways :

  Microbiology/Virology|||Proteases/Proteasome|||Membrane transporter/Ion channel

• Bioactivity :

  Concanamycin A (Folimycin), a polycyclic lactone antibiotic, is a selective inhibitor of vacuolar H+-ATPase (V-ATPase) and lysosomal acidification, and can be used to study inflammation.Concanamycin A enhances the immune clearance of infected progenitor cells by cytotoxic T lymphocytes, and inhibits Nef et al. from different branches of HIV and simian immunodeficiency virus. Concanamycin A enhances immune clearance of cytotoxic T lymphocytes from infected progenitor cells, inhibits the Nef allele from different branches of HIV and simian immunodeficiency virus, and can be used to study HIV infection.

• Smiles :

  [H][C@@]1(C[C@@H](O)[C@H](OC(N)=O)[C@@H](C)O1)O[C@@H]1C[C@@](O)(O[C@H](\C=C\C)[C@H]1C)[C@@H](C)[C@H](O)[C@H](C)[C@@]1([H])OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@H](O)[C@@H](CC)[C@H](O)[C@H](C)C\C(C)=C\C=C\[C@@H]1OC

• Molecular Formula :

  C46H75NO14

• Molecular Weight :

  866.09

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  80890-47-7