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Agerafenib hydrochloride

CAT: 0931-T14928-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T14928-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1227678-26-3
Target
C-Kit, Raf, c-RET
Related Pathways
Tyrosine Kinase/Adaptors, MAPK, Apoptosis
Bioactivity
Agerafenib hydrochloride, a highly potent inhibitor of BRAFV600E (Kd: 14 nM), demonstrates significant efficacy.
Smiles
Cl.COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1OC
Molecular Formula
C24H23ClF3N5O5
Molecular Weight
553.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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