CCT367766

• Target :

  PROTACs

• Related Pathways :

  PROTAC

• Purity :

  >99.99%

• Bioactivity :

  CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low concentrations.

• Smiles :

  O=C(NC1=CC=C(Cl)C(=C1)NC(=O)C=2C=CC=3N=C(C=CC3C2)CN4CCN(CCOCCOCCOC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4)C8=CC=C9OCCOC9=C8

• Molecular Formula :

  C49H48ClN7O11

• Molecular Weight :

  946.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2229856-58-8