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CCT367766

CAT: 0931-T14908-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14908-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2229856-58-8
Target
PROTACs
Related Pathways
PROTAC
Purity
>99.99%
Bioactivity
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low concentrations.
Smiles
O=C(NC1=CC=C(Cl)C(=C1)NC(=O)C=2C=CC=3N=C(C=CC3C2)CN4CCN(CCOCCOCCOC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4)C8=CC=C9OCCOC9=C8
Molecular Formula
C49H48ClN7O11
Molecular Weight
946.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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