Carboxyamidotriazole

CAT: 0931-T14872-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T14872-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

99519-84-3

Target

P38 MAPK, NF-κB, Calcium Channel, NO Synthase

Related Pathways

NF-κB, Metabolism, Membrane transporter/Ion channel, MAPK, Immunology/Inflammation

Bioactivity

Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects.

Smiles

NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N

Molecular Formula

C17H12Cl3N5O2

Molecular Weight

424.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Carboxyamidotriazole

Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.

CAS Number	99519-84-3
PubChem CID	108144
IUPAC Name	5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]triazole-4-carboxamide
Molecular Formula	C17H12Cl3N5O2
Molecular Weight	424.7
XLogP	3.9
Topological Polar Surface Area	117
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Heavy Atom Count	27
Formal Charge	0
Complexity	549

SMILES

C1=CC(=CC=C1C(=O)C2=C(C=C(C=C2Cl)CN3C(=C(N=N3)C(=O)N)N)Cl)Cl

InChI

InChI=1S/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27)

InChIKey

WNRZHQBJSXRYJK-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 99519-84-3

CID: 108144

Formula: C17H12Cl3N5O2

MW: 424.7

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	424.7
XLogP3	3.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	423.005658
Monoisotopic Mass	423.005658
Topological Polar Surface Area	117 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	549
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
TRC-C177775-50MG	Carboxyamidotriazole
HY-16125-01	Carboxyamidotriazole (Orotate)
A20940-50	Carboxyamidotriazole 50mg
A20940-1	Carboxyamidotriazole 1mg
C09006-25mg	CarboxyaMidotriazole orotate
A20940-25	Carboxyamidotriazole 25mg
AR-C06181-01	Carboxyamidotriazole-d6
A20940-10	Carboxyamidotriazole 10mg
A20940-5	Carboxyamidotriazole 5mg

Carboxyamidotriazole

Chemical Information

Alternative Products

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