Calicheamicin

• Target:

  DNA Alkylator/Crosslinker|||Apoptosis|||ADC Cytotoxin|||Antibacterial|||Antibiotic

• Related Pathways:

  Microbiology/Virology|||Apoptosis|||Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Purity:

  0.9878

• Bioactivity:

  Calicheamicin (Calicheamicin ?1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.

• Smiles:

  [H][C@@]1(C[C@H](OC)[C@H](CO1)NCC)O[C@@H]1[C@@H](O)[C@H](NO[C@H]2C[C@H](O)[C@H](SC(=O)c3c(C)c(I)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC)[C@H]4O)c(OC)c3OC)[C@@H](C)O2)[C@@H](C)O[C@@]1([H])O[C@H]1C#C\C=C/C#C[C@]2(O)CC(=O)C(NC(=O)OC)=C1\C2=C\CSSSC

• Molecular Formula:

  C55H74IN3O21S4

• Molecular Weight:

  1368.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  108212-75-5