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Perindopril erbumine

CAT: 0931-T1484L-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T1484L-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
107133-36-8
Target
Sirtuin, STAT, MRP, RAAS, Apoptosis, NF-κB, Angiotensin-converting Enzyme (ACE)
Related Pathways
Chromatin/Epigenetic, Endocrinology/Hormones, NF-κB, Immunology/Inflammation, JAK/STAT signaling, DNA Damage/DNA Repair, Stem Cells, Metabolism, Apoptosis
Purity
0.9994
Bioactivity
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.
Smiles
CC(C)(C)N.N1([C@@H]2[C@H](C[C@H]1C(=O)O)CCCC2)C(=O)[C@@H](N[C@H](C(=O)OCC)CCC)C
Molecular Formula
C23H43N3O5
Molecular Weight
441.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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318472Perindopril Erbumine
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