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Bryostatin 1

CAT: 0931-T14831Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0931-T14831Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83314-01-6
Target
HIV Protease, PKC, Antibacterial
Related Pathways
Proteases/Proteasome, Microbiology/Virology, Chromatin/Epigenetic, Cytoskeletal Signaling
Bioactivity
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein [Kis: 8.07 nM and 0.45 nM].
Smiles
O[C@]12[C@@H](OC(/C=C/C=C/CCC)=O)\C(=C\C(OC)=O)\C[C@](O1)(C[C@]([C@@H](C)O)(OC(=O)C[C@H](O)C[C@]3(O[C@@](O)(C[C@]4(O[C@@](\C=C\C2(C)C)(C/C(=C\C(OC)=O)/C4)[H])[H])C(C)(C)[C@@H](OC(C)=O)C3)[H])[H])[H]
Molecular Formula
C47H68O17
Molecular Weight
905.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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