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Brilaroxazine

CAT: 0931-T14782-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14782-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1239729-06-6
Target
Dopamine Receptor, 5-HT Receptor
Related Pathways
GPCR/G Protein, Neuroscience
Purity
0.9936
Bioactivity
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-HT2B, and 5-HT7 receptors with Kis of 0.19 nM and 2.7 nM, respectively. Brilaroxazine can be used for research about cognitive impairments in neuropsychiatric and neurological diseases.
Smiles
Clc1cccc(N2CCN(CCCCOc3ccc4OCC(=O)Nc4c3)CC2)c1Cl
Molecular Formula
C22H25Cl2N3O3
Molecular Weight
450.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C