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BN201

CAT: 0931-T14693-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T14693-05Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1361200-34-1
Target
Others, FOXO, SGK, IGF-1R
Related Pathways
Others, Tyrosine Kinase/Adaptors, Apoptosis, Metabolism
Purity
0.9973
Bioactivity
BN201 (OCS-05) is a drug with neuroprotective and myelin repair effects, which acts mainly by activating serum glucocorticoid kinase-2 (SGK2), which in turn activates the FOXO3 pathway to promote neuronal survival and myelin repair. It is mainly used for the treatment of inflammatory neurological diseases such as multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) .BN201 is able to regulate multiple kinases in the insulin growth factor 1 (IGF1) pathway and cross the blood-brain barrier.
Smiles
O=C(N)CN(C(=O)CN(C(=O)CNCCC=1C=CC=CC1F)CC(C)C)CCCN2C(=O)CCC2
Molecular Formula
C25H38FN5O4
Molecular Weight
491.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

BN-201
CAS Number1361200-34-1
PubChem CID66610682
IUPAC NameN-[2-[(2-amino-2-oxoethyl)-[3-(2-oxopyrrolidin-1-yl)propyl]amino]-2-oxoethyl]-2-[2-(2-fluorophenyl)ethylamino]-N-(2-methylpropyl)acetamide
Molecular FormulaC25H38FN5O4
Molecular Weight491.6
XLogP1.1
Topological Polar Surface Area116
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count15
Heavy Atom Count35
Formal Charge0
Complexity720
SMILES
CC(C)CN(CC(=O)N(CCCN1CCCC1=O)CC(=O)N)C(=O)CNCCC2=CC=CC=C2F
InChI
InChI=1S/C25H38FN5O4/c1-19(2)16-31(24(34)15-28-11-10-20-7-3-4-8-21(20)26)18-25(35)30(17-22(27)32)14-6-13-29-12-5-9-23(29)33/h3-4,7-8,19,28H,5-6,9-18H2,1-2H3,(H2,27,32)
InChIKey
ODCKWAPNRBCXHV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of BN-201
CAS: 1361200-34-1
CID: 66610682
Formula: C25H38FN5O4
MW: 491.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight491.6
XLogP31.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count15
Exact Mass491.29078287
Monoisotopic Mass491.29078287
Topological Polar Surface Area116 Ų
Heavy Atom Count35
Formal Charge0
Complexity720
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BUP21011-01BN201

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