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BIIE-0246

CAT: 0931-T14572Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T14572Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
246146-55-4
Target
Neuropeptide Y Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
BIIE-0246 is a selective NPY2R antagonist with an IC50 of 15 nM at the rat [125I]PYY3-36 site. It reduces NPY-stimulated expression of p-AKT S473 and P-p44/42 MAPK.
Smiles
O=C1C=2C(C(C=3C(N1)=CC=CC3)N4CCN(C(CC5(CC(N[C@H](C(NCCN6C(=O)N(N(C6=O)C7=CC=CC=C7)C8=CC=CC=C8)=O)CCCNC(=N)N)=O)CCCC5)=O)CC4)=CC=CC2
Molecular Formula
C49H57N11O6
Molecular Weight
896.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-101986-01BIIE-0246
A12158-100BIIE 0246 100mg
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HY-101986CBIIE-0246 (dihydrochloride)
A12158-50BIIE 0246 50mg
A12158-5BIIE 0246 5mg
HY-101986ABIIE-0246 (hydrochloride)
A12158-25BIIE 0246 25mg

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