Doxorubicin

• Target:

  AMPK|||ADC Cytotoxin|||Topoisomerase

• Related Pathways:

  Antibody-drug Conjugate/ADC Related|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

• Purity:

  0.9931

• Bioactivity:

  Doxorubicin (Adriamycin) is a fluorescent anthracycline antitumor antibiotic that inhibits Topoisomerase I/II, induces apoptosis and autophagy, downregulates the AMPK signaling pathway, and is commonly used in cancer chemotherapy as well as in models of nephritis and heart failure.

• Smiles:

  COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

• Molecular Formula:

  C27H29NO11

• Molecular Weight:

  543.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  23214-92-8