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Doxorubicin

CAT: 0931-T1456-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T1456-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
23214-92-8
Target
AMPK, ADC Cytotoxin, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
0.9931
Bioactivity
Doxorubicin (Adriamycin) is a fluorescent anthracycline antitumor antibiotic that inhibits Topoisomerase I/II, induces apoptosis and autophagy, downregulates the AMPK signaling pathway, and is commonly used in cancer chemotherapy as well as in models of nephritis and heart failure.
Smiles
COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
Molecular Formula
C27H29NO11
Molecular Weight
543.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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