Axitinib

• CAS Number :

  319460-85-0

• Target :

  PDGFR|||VEGFR|||c-Kit

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9981

• Bioactivity :

  Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFR? (IC50=4/20/0.4/2 nM) . Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.

• Smiles :

  C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2

• Molecular Formula :

  C22H18N4OS

• Molecular Weight :

  386.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C