Axitinib

• Target:

  PDGFR|||VEGFR|||c-Kit

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9981

• Bioactivity:

  Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFR? (IC50=4/20/0.4/2 nM) . Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.

• Smiles:

  C (=C/C1=CC=CC=N1) \C=2C=3C (=CC (SC4=C (C (NC) =O) C=CC=C4) =CC3) NN2

• Molecular Formula:

  C22H18N4OS

• Molecular Weight:

  386.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  319460-85-0