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Levofloxacin hydrate

CAT: 0931-T1451-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T1451-01Size:1 mL - 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
138199-71-0
Target
DNA/RNA Synthesis, DNA gyrase, Topoisomerase, Virus Protease, Antibacterial, Antibiotic
Related Pathways
Microbiology/Virology, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.9856
Bioactivity
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
Smiles
O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O
Molecular Formula
C18H20FN3O4·1/2H2O
Molecular Weight
370.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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