AZD5582

• Target:

  Apoptosis|||IAP

• Related Pathways:

  Apoptosis

• Purity:

  >99.99%

• Bioactivity:

  AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.

• Smiles:

  OC(=O)C(F)(F)F.CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1[C@@H](Cc2ccccc12)OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C1CCCCC1

• Molecular Formula:

  C58H78N8O8

• Molecular Weight:

  1015.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1258392-53-8